The research, published in the Journal of Clinical Immunology and Immunotherapy, indicates that besides the loss of taste and smell, headaches that occur in the days before the onset of Coughing and difficulty breathing, and some sufferers have increased delirium.
Mental confusion accompanied by a fever may be an early symptom of COVID-19.
London:
Delirium or intellectual confusion accompanied by fever may also be an early symptom of COVID-19, especially in elderly patients, according to studies evaluation.
The research, published in the Journal of Clinical Immunology and Immunotherapy, indicates that along with the loss of taste and smell, headaches that occur in the days before the onset of Coughing and difficulty breathing, and some sufferers have increased delirium.
As such, the appearance of this state of disorientation, when accompanied by a rise in temperature, should be considered an early sign of disease, especially in the case of elderly patients.
"Delirium is a state of disorientation in which a person feels distant from reality as if he is dreaming," explained Javier Correa of the University of Uberta de Catalunya (UOC) in Spain.
Correa, who conducted the study at Bordeaux University in France, said, "We need to be alert, especially in an epidemic situation like this, because an individual who shows certain signs of confusion may be an indicator of infection."
Correa, along with University of British Columbia researcher Diego Ridollar Ripoll, reviewed published scientific work on the effects of COVID-19 in relation to the central nervous system, the brain.
The review found that there are increasing indications that the new Corona virus is also affecting the central nervous system, resulting in neurocognitive changes, such as headaches and delirium, in addition to psychotic attacks.
The main hypotheses explaining how SARS-CoV-2 affects the brain indicate three possible causes: hypoxia or neural hypoxia, inflammation of brain tissue due to a cytokine storm and the fact The virus has the ability to cross the blood intelligence barrier and invade the brain at once. Correa said.
He noted that any of these three factors could trigger delirium.
Correa said that evidence of brain damage related to hypoxia had been observed in autopsies performed on patients who had died from infection, and the virus could have been isolated from brain tissue.
According to the researchers, delirium, cognitive deficits, and behavioral anomalies are likely due to a systemic infection in the organ and the kingdom of hypoxia, which also leads to irritation of nerve tissue and causes damage to areas such as the hippocampus.
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