Mucosal immunity may play an "important role" in preventing transmission of the Coronavirus: experts

 

The analysis indicated that the mucosal immune system is the largest component of immunity, but it has not been the focus of much research on COVID-19 so far.

New York:

The mucous membranes of the nose and mouth may play an "important role" in limiting the spread of COVID-19, say scientists who are calling for more studies to assess the role this arm plays in the immune system in mild and asymptomatic cases of the Coronavirus. infection.

The analysis, published in Frontiers in Immunology, indicated that the mucosal immune system is the largest component of immunity, but it hasn't been the focus of much research on COVID-19 yet.

"We are counting that skipping the mucosal immune response to SARS-CoV-2 is a serious overlook, given the most prevalent contamination network sites," said Michael W. Russell, co-author at the University of Buffalo, USA.

Russell added, "It is clear that the systemic response of the IgG antibody - the most common antibody - is important, and we are no longer denying that, but in itself it is no longer sufficient."

He said the primary focus of COVID-19 research was on cases of severe illness when the virus descended into the lower respiratory tract, especially the lungs.

The scientists said that cellular immune responses in the lungs exacerbate inflammation rather than fight infection.

But since the upper respiratory tract, including the nose, tonsils, and adenoids is the primary point of SARS-CoV-2 infection, they said that the immune responses triggered there are of particular importance.

Researchers are confident that the overcharging of asymptomatic transmission of COVID-19 is any other reason why mucosal immunity is so important.

Russell said: "Given that many of these pollutants are not showing symptoms now, and that a large group of those who have signs only have mild to moderate symptoms of disease, this indicates that something, somewhere, is doing a very delicate job." In controlling the virus. "