Dr. Kaneganti was born and raised in Telangana. She obtained her undergraduate degree from Kakatia University, Warangal, where she majored in chemistry, zoology and botany. Then I got my master's degree. And a doctorate from Othmania University. She joined Saint Jude, in Memphis, Tennessee, USA, in 2007.
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| Indian-American physician |
Washington:
An Indian-American physician and scientist has discovered a potential strategy to prevent life-threatening infections, lung damage, and organ failure in patients diagnosed with COVID-19.
Published online in the journal Cell, the research is by the lab of Dr. Thirumala-Devi Kanneganti, an Indian-born researcher working at St. Jude Children's Research Hospital in Tennessee, and identified drugs after discovering that the highly inflammatory immune response associated with COVID-19 leads To tissue damage and multiple organ failure in mice by stimulating inflammatory cell death pathways.
Researchers have detailed how the inflammatory cell death signaling pathway works, leading to potential treatments to disrupt the process.
"Understanding the pathways and mechanisms that drive this inflammation is critical for developing effective treatment strategies," said Dr. Kanneganti, St Jude's Vice President of Immunology.
Dr. Kaneganti was born and raised in Telangana. She obtained her undergraduate degree from Kakatia University in Warangal, where she majored in chemistry, zoology and botany. Then I got my master's degree. Ph.D. from the Ottoman University in India. She joined Saint Jude, in Memphis, Tennessee, USA, in 2007.
"This research provides this understanding. We've also recognized unique cytokines that trigger the elimination pathways of cell phone infections and are exceptionally achievable for treating COVID-19 and various very deadly diseases, which include sepsis.
Other researchers are Shraddha Tolladhar, Parimal Samir, Min Zeng, Palamorgan Sundaram, Balaji Banoth, RK Subarao Malerdy, Patrick Schreiner, Geoffrey Neal, Peter Vogel and Richard Webby, from Saint Jude. Evan Peter Williams, Lillian Zaldondo, and Colin Beth Johnson from the University of Tennessee Health Sciences Center.
COVID-19 is caused by the SARS-CoV-2 virus. The infection has killed more than 1.2 million people in less than one year and sickened millions of others.
The infection is characterized by increased levels of multiple cytokines in the blood. Immune cells essentially secrete these small proteins to ensure a fast response to virus restriction. Some cytokines also cause inflammation.
The term cytokine storm has been used to describe the significantly elevated cytokine levels in the blood and other immune changes that have also been observed in COVID-19.
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